Stanca M. Ciupe
Assistant Professor

Contact:
Office: 433 Maxim Doucet
Phone: 337-482-5287
E-mail: msc6503@louisiana.edu
Home page: not available

Degrees:
Ph.D. 2005 University of Michigan, Ann Arbor
M.S. 1998 Babes-Bolyai University, Cluj-Napoca, Romania
B.A. 1997 Babes-Bolyai University, Cluj-Napoca, Romania

Statement:
My research interest is in the field of applied mathematics, specifically, systems of delay differential equations and their application to biology and medicine. My research has focused on understanding the possible homeostatic mechanisms regulating lymphocyte population sizes and their T cell receptor diversity and on the characterization of immune system onset and reaction against viral diseases like Human ImmunodeficiencyVirus infection, Hepatitis B and Dengue viral infections.

Selected research publications:

• The dynamics of T-cell receptor repertoire diversity following thymus transplantation for DiGeorge Anomaly (with Blythe H. Devlin, M. Louise Markert, and Thomas B. Kepler), PLoS Computational Biology, (2009), to appear.
• Modeling dynamic fluctuations in type 1diabetes progression (with P.W. Nelson, N. Smith, W. Zou, G.S. Omenn, and M. Pietropaolo), submitted.
• Dynamics of hepatitis b virus infection: what causes viral clearance? (with Anne Catlla, Jonathan Forde, and David G. Schaeffer), submitted.
• The role of cells refractory to productive infection in acute hepatitis B viral dynamics (with Ruy M. Ribeiro, Patrick W. Nelson, Geoffrey Dusheiko, and Alan S. Perelson), Proc. Natl. Acad. Sci. USA, 104 (2007), 5050­5055.
• Modeling the mechanisms of acute hepatitis B virus infection (with Ruy Ribeiro, Patrick Nelson, and Alan Perelson), J. Theoret. Biol., 247 (2007), 23-35.
• Estimating kinetic parameters from HIV primary infection data through the eyes of three different mathematical models (with B.L. Bivort, D.M. Bortz, and P.W. Nelson), Math. Biosci., 200 (2006), 1-27.